As an industry leader in lipid delivery technology, Scindy Pharmaceutical leverages its proprietary advanced lipid material platform to achieve breakthrough applications of LNP (Lipid Nanoparticle) technology. We proudly introduce a series of innovative cell transfection products based on LNP technology, marking a new era of precise and efficient RNA delivery by systematically applying LNP technology to in vitro transfection.

The NeoLNP? RNA Transfection Kit for Common Cells (SDR8006) is designed for common cell lines, offering an efficient and reliable transfection solution that simplifies and accelerates RNA research in these cells.

NeoLNP? SDR8006: Superior RNA Delivery Performance, Broadly Applicable to Common Cells

High Cell Expression: SDR8006 achieves efficient intracellular delivery through unique transmembrane transport and endosomal escape mechanisms, easily achieving transfection efficiencies above 90%.

Compatible with Various RNA Types: Suitable for transfecting mRNA, siRNA, gRNA, saRNA, circRNA, and other RNA types.

Messenger RNA (mRNA):

* Using a 24-well plate, transfect with eGFP mRNA, followed by fluorescence imaging and flow cytometry analysis after 24 hours.

Small Interfering RNA (siRNA) - Cellular Uptake Efficiency:

* Transfect with 30nM Cy3-labeled siRNA per well, followed by fluorescence imaging after 6 hours.

Small Interfering RNA (siRNA) - Gene Silencing Efficiency

* Transfect with 30nM GAPDH siRNA per well, followed by qPCR analysis after 48 hours to measure GAPDH mRNA relative expression levels.

Circular RNA (circRNA):

* Using a 96-well plate, transfect with 100ng eGFP circRNA per well, followed by fluorescence imaging after 24 hours.

Self-Amplifying RNA (saRNA):

* Using a 96-well plate, transfect with 100ng eGFP saRNA per well, followed by fluorescence imaging after 24 hours.

Extremely Low Cytotoxicity: Utilizes biodegradable materials, free of ethanol, with minimal impact on cells, reducing experimental bias. After transfecting 30nM GAPDH siRNA into 293T cells, cell proliferation activity is assessed using a CCK-8 kit after 24 hours.

Broad Cell Compatibility: Successfully validated in over 100 cell types, including A549, Capan-2, and HEK293, with most achieving transfection efficiencies exceeding 90%. SDR8006 far surpasses industry standards.

NeoLNP? Simple and User-Friendly RNA-LNP Encapsulation Solution The NeoLNP?

Transfection Kit offers an innovative RNA-LNP encapsulation solution. Compared to traditional methods, NeoLNP? requires no complex equipment, achieving zero-loss RNA encapsulation through a simple one-step mixing process, significantly reducing preparation time (1 minute vs. 10 hours). This technology overcomes the technical barriers of traditional LNP preparation, delivering optimized, standardized LNP formulations to researchers, providing a new experience for RNA transfection.